Brain Matters

from Fernandez

If drenching sweats, especially at night, are part of an off phenomenon due to the long gap between the last dopaminergic dose at night and the first dose the next morning, adding sustained-release levodopa (such as Sinemet CR) at bedtime may be considered. Otherwise, propranolol or clonidine may be also considered if Parkinson's disease medication adjustments do not relieve the drenching sweats.